期刊
VACCINE
卷 24, 期 -, 页码 155-163出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2006.05.112
关键词
decision science; economic evaluation; mathematical modeling; HPV
资金
- NCI NIH HHS [R01 CA 093435] Funding Source: Medline
Several factors are changing the landscape of cervical cancer control, including a better understanding of the natural history of human papillomavirus (HPV), reliable assays for detecting high-risk HPV infections, and a soon to be available HPV-16/18 vaccine. There are important differences in the relevant policy questions for different settings. By synthesizing and integrating the best available data, the use of modeling in a decision analytic framework can identify those factors most likely to influence outcomes, can guide the design of future clinical studies and operational research, can provide insight into the cost-effectiveness of different strategies, and can assist in early decision-making when considered with criteria such as equity, public preferences, and political and cultural constraints. (c) 2006 Elsevier Ltd. All rights reserved.
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