期刊
BIOELECTROCHEMISTRY
卷 69, 期 1, 页码 82-87出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.bioelechem.2005.10.006
关键词
adriamycin; doxorubicin; kinetics; redox reaction; surface; graphite electrode; mercury electrode; square-wave voltammetry
Kinetics of the surface redox reactions of adriamycin (doxorubicin hydrochloride) adsorbed on paraffin-impregnated graphite electrode (PIGE) and on mercury electrode is measured by square-wave voltammetry. In 0.9 mol/L KNO3 buffered to pH 4.65, the standard electrode reaction rate constants of the first quinone/hydroquinone redox couple (see Scheme 2) on PIGE and mercury are k(sl)=49 +/- 12 s(-1) and k(sl)=147 +/- 36 s(-1), respectively. Under the same conditions, the standard rate constant of the second redox couple on the PIGE is smaller than 4 s(-1) and the electron transfer coefficient of the reduction is alpha(2)=0.35. (c) 2005 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据