期刊
JOURNAL OF MATHEMATICAL BIOLOGY
卷 53, 期 3, 页码 421-436出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00285-006-0015-0
关键词
vector-borne disease; seasonality; epidemic threshold
Cutaneous leishmaniasis is a vector-borne disease transmitted to humans by sandflies. In this paper, we develop a mathematical model which takes into account the seasonality of the vector population and the distribution of the latent period from infection to symptoms in humans. Parameters are fitted to real data from the province of Chichaoua, Morocco. We also introduce a generalization of the definition of the basic reproduction number R-0 which is adapted to periodic environments. This R-0 is estimated numerically for the epidemic in Chichaoua; R-0 similar or equal to 1.94. The model suggests that the epidemic could be stopped if the vector population were reduced by a factor (R-0)(2) similar or equal to 3.76.
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