期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 12, 期 26, 页码 6730-6737出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.200600370
关键词
cyclodextrins; gene carriers; molecular recognition; polymers; polyrotaxanes
Cyclic compounds can rotate and/or slide along a polymeric chain in a polyrotaxane structure, and the mobility of the ligands linked by the cyclic compounds is closely related to enhancing the multivalent interaction with binding sites on the receptor proteins. This concept is being exploited in more practical applications in the biomedical and pharmaceutical fields, such as a non-viral gene carriers.
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