期刊
TETRAHEDRON
卷 62, 期 39, 页码 9201-9209出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2006.07.031
关键词
-
Dehydrative Friedel-Crafts acylation reaction of aromatic compounds with carboxylic acids as acylating agents was investigated in the presence of Lewis acid- or Bronsted acid-catalyst. Various metal triflates and bis(trifluoromethanesulfonyl)amides showed catalytic activity at high temperature, among which Eu(NTf2)(3) proved to be the most effective and efficiently catalyzed the acylation reaction of alkyl- and alkoxybenzenes with aliphatic and aromatic carboxylic acids at 250 degrees C. Bi(NTf2)(3) was more effective than Eu(NTf2)(3) at lower temperature, but proved to be hydrolyzed in the presence of a small amount of water to give HNTf2 and [Bi6O4(OH)(4)(H2O)(6])(NTf2)(6). The structure of the latter compound was confirmed by a single crystal X-ray analysis. Among five Bronsted acids, HOTf, HNTf2, HCTf3, TsOH, and Nafion (R) SAC-13, HNTf2 has proved to be the most efficient catalyst and more effective than Eu(NTf2)(3) for the acylation of p-xylene with heptanoic acid at 220 degrees C or lower temperature. HNTf2 catalyzed the acylation of anisole with carboxylic acids in high yields in refluxing toluene with azeotropic removal of water. (c) 2006 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据