期刊
JOURNAL OF NEUROSCIENCE METHODS
卷 156, 期 1-2, 页码 140-144出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jneumeth.2006.02.019
关键词
bone afferent nerves; bone pain; periosteal nociceptors; peripheral nerve; sensory nerve fibres
A preparation is described in which it is possible to selectively activate and monitor the activity of the individual periosteal afferent nerve fibres arising from the humerus bone of the cat. The nerve is a fine branch of the median nerve that accompanies the small artery and vein that enter the nutrient foramen of the humerus. By freeing this fine nerve from nearby tissue over a length of similar to 1-2 cm and placing it over a silver hook recording electrode, it becomes possible to identify and monitor electrophysiologically, the impulse activity of individual periosteal afferent fibres activated by focal mechanical stimulation of the periosteum. With this preparation it will be possible to examine the central actions and security of transmission at central synaptic targets for single, small-diameter afferent fibres arising from bone. (c) 2006 Elsevier B.V. All rights reserved.
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