期刊
GENES & GENETIC SYSTEMS
卷 81, 期 5, 页码 367-371出版社
GENETICS SOC JAPAN
DOI: 10.1266/ggs.81.367
关键词
alpha- beta-globin gene family; standardized nomenclature
The globin family of genes and proteins has been a recurrent object of study for many decades. This interest has generated a vast amount of knowledge. However it has also created an inconsistent and confusing nomenclature, due to the lack of a systematic approach to naming genes and failure to reflect the phylogenetic relationships among genes of the gene family. To alleviate the problems with the existing system, here we propose a standardized nomenclature for the alpha and beta globin family of genes, based on a phylogenetic analysis of vertebrate alpha and beta globins, and following the Guidelines for Human Gene Nomenclature.
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