期刊
CLINICAL AND VACCINE IMMUNOLOGY
卷 13, 期 10, 页码 1162-1165出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/CVI.00099-06
关键词
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The OspC protein of Borrelia burgdorferi is an immunodominant antigen. Here we demonstrate that the loop 5 domain of type A OspC is surface exposed, elicits bactericidal antibody in mice, and is antigenic in humans. The data suggest that loop 5 may be suitable for inclusion in a polyvalent, chimeric OspC vaccinogen.
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