期刊
CURRENT OPINION IN CELL BIOLOGY
卷 18, 期 5, 页码 572-578出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2006.07.002
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资金
- NIGMS NIH HHS [R37 GM37432, R01 GM052717] Funding Source: Medline
Cell adhesion molecules mediate cell-cell and cellextracellular matrix adhesions, and coordination between these molecules is essential for tissue formation and morphogenesis. Crosstalk between integrins and cadherins may result from a physical response to integrin-mediated adhesion, complex cell differentiation processes, or direct signaling pathways linking the two adhesion systems. Nectins have recently been shown to regulate the organization of cadherins into adherens junctions and the formation of tight junctions by several processes. Furthermore, protocadherins can interact with extracellular matrix proteins or function by regulating classical cadherins.
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