期刊
BRITISH JOURNAL OF DERMATOLOGY
卷 155, 期 4, 页码 827-829出版社
BLACKWELL PUBLISHING
DOI: 10.1111/j.1365-2133.2006.07417.x
关键词
marginal zone lymphoma; monoclonal gammopathy; Schnitzler syndrome
类别
Schnitzler syndrome is a rare condition defined by chronic urticaria and monoclonal IgM gammopathy. Malignant evolution to Waldenstrom disease (WD) has been reported in several cases. We report a 49-year-old man who developed a marginal zone B-cell lymphoma (MZL) 3 years after the beginning of Schnitzler syndrome. This is the first report of MZL in association with Schnitzler syndrome. IgM gammopathy is a clue for the diagnosis of Schnitzler syndrome. This condition needs to be closely monitored; it can precede the onset of an authentic lymphoproliferative disorder including WD and rarely MZL.
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