期刊
TRENDS IN ECOLOGY & EVOLUTION
卷 21, 期 10, 页码 569-575出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tree.2006.06.015
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资金
- Biotechnology and Biological Sciences Research Council [BB/C517784/1] Funding Source: Medline
- Biotechnology and Biological Sciences Research Council [BB/C517784/1] Funding Source: researchfish
The role of positive darwinian selection in evolution at the molecular level has been keenly debated for many years, with little resolution. However, a recent increase in DNA sequence data and the development of new methods of analysis have finally made this question tractable. Here, I review the current state-of-play of the field. Initial estimates in Drosophila suggest that similar to 50% of all amino acid substitutions, and a substantial fraction of substitutions in non-coding DNA, have been fixed as a consequence of adaptive evolution. Estimates in microorganisms are even higher. By contrast, there is little evidence of widespread adaptive evolution in our own species.
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