期刊
EXERCISE AND SPORT SCIENCES REVIEWS
卷 34, 期 4, 页码 176-181出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1249/01.jes.0000240027.22749.14
关键词
inflammation; toll-like receptor 4; anti-inflammatory; lipopolysaccharide; physical activity
资金
- NIA NIH HHS [1R03AG022185-01] Funding Source: Medline
Evidence is emerging that exercise training has anti-inflammatory effects. Our early finding that blood cultures from trained subject had a reduced responsiveness to lipopolysaccharide led to a series of studies in which we measured toll-like receptor 4-the primary signaling receptor for lipopolysaccharide. The toll-like receptor 4 expression was consistently lower in physically active subjects compared with inactive subjects and reduced after training in previously inactive subjects.
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