Concise review: Scientific and ethical roadblocks to human embryonic stem cell therapy

Despite the identified therapeutic potential of embryonic stem cells for treating human disease and injury, a number of roadblocks, scientific and ethical, stand in the way of progress toward this goal. We identify six areas of particular interest: tumorigenicity, animal product contamination, genetic compatibility, funding, cell type for transplantation, embryo-friendly derivation methods and discuss avenues for moving beyond the difficulties.