Management of endometrial cancer

Aim: To review broadly the diagnosis and treatment of endometrial cancer, concentrating on the evidence base. Methods: The peer reviewed literature has been cited selectively to support the principal themes of the review. Results: A rising incidence of endometrial cancer will continue to present challenges to improve survival particularly for high-risk and advanced disease. Lymphadenectomy and adjuvant radiotherapy are and will be used more rationally as evidence for their effectiveness accumulates. Conclusions: The area of greatest need in endometrial cancer is now to improve outcomes for women with advanced/recurrent disease. (c) 2006 Elsevier Ltd. All rights reserved.