期刊
ANNALS OF BIOMEDICAL ENGINEERING
卷 42, 期 2, 页码 388-404出版社
SPRINGER
DOI: 10.1007/s10439-013-0904-5
关键词
Single molecule; Conformational change; Catch bond; Cyclic mechanical reinforcement
资金
- National Institutes of Health [AI077343, AI44902, AI038282, HL093723, HL091020, GM096187, TW008753]
Molecular biomechanics includes two themes: the study of mechanical aspects of biomolecules and the study of molecular biology of the cell using mechanical tools. The two themes are interconnected for obvious reasons. The present review focuses on one of the interconnected areas-the mechanical regulation of molecular interaction and conformational change. Recent conceptual developments are summarized, including catch bonds, regulation of molecular interaction by the history of force application, and cyclic mechanical reinforcement. These studies elucidate the mechanochemistry of some of the candidate mechanosensing molecules, thereby providing a natural connection to mechanobiology.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据