4.6 Article

Quantification of the roles of trabecular microarchitecture and trabecular type in determining the elastic modulus of human trabecular bone

期刊

JOURNAL OF BONE AND MINERAL RESEARCH
卷 21, 期 10, 页码 1608-1617

出版社

WILEY
DOI: 10.1359/JBMR.060716

关键词

osteoporosis; microarchitecture; trabecular type; digital topology; mu CT imaging

资金

  1. NIAMS NIH HHS [AR051376, R21 AR049613, R01 AR041443, R01 AR049553, R01 AR051376, AR041443, AR049553, R01 AR051376-01A1, R01 AR048287, AR049613, AR048287] Funding Source: Medline

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The roles of microarchitecture and types of trabeculae in determining elastic modulus of trabecular bone have been studied in mu CT images of 29 trabecular bone samples by comparing their Young's moduli calculated by finite element analysis (FEA) with different trabecular type-specific reconstructions. The results suggest that trabecular plates play an essential role in determining elastic properties of trabecular bone.

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