期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 50, 期 10, 页码 3467-3469出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00670-06
关键词
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Ambruticin S, an antifungal cyclopropyl-pyran acid, showed curative effects against murine coccidioidal infection. Two analogs of this compound with greater in vitro potency were tested against lethal murine Coccidioides infection. Both improved the survival of mice over that of controls; one resulted in near-sterilization of infection.
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