期刊
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
卷 48, 期 10, 页码 1014-1022出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.jom.0000237773.26755.78
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Objective: The objective of this study was to examine the impact of introducing rosuvastatin calcium on direct and indirect costs among patients at high risk for coronary heart disease. Methods: An economic simulation model was developed to project the number of cardiovascular events and associated direct and indirect costs under varying treatment scenarios. Results: In an average-sized commercial health plan with 210,000 covered lives and 9,336 high-risk patients, an uptake of rosuvastatin by 11% of high-risk patients would result in eight fewer cardiovascular events, a net savings of $0.85 million in direct medical costs and a net savings of $36,404 in productivity loss over a period of 5 years. The overall reduction in total costs is equivalent to $1735 per rosuvastatin-treated patient. Conclusions: At current statin prices, the use of rosuvastatin could lead to fewer cardiovascular events and lower direct and indirect costs.
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