期刊
ADVANCED DRUG DELIVERY REVIEWS
卷 58, 期 8, 页码 902-915出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.addr.2006.05.004
关键词
immunotherapy; immune evasion; tumour vaccines
The first generation of human cancer vaccines has been tested in phase III clinical trials, but only a few of these have demonstrated sufficient efficacy to be licensed for clinical use. This article reviews some of the mechanisms that could contribute to these limited clinical responses, and highlights the challenges faced for development of future vaccines. (c) 2006 Elsevier B.V. All rights reserved.
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