期刊
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
卷 28, 期 10, 页码 688-692出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.mph.0000212992.72059.eb
关键词
germ cell tumor; teratoma with malignant transformation; rhabdomyosarcoma; childhood; testicular cancer
Background: The somatic type tumors are occasionally found in nonseminomatous germ cell tumors in men. These malignancies are presumed to arise from malignant transformation (MT) of teratoma or by differentiation of totipotential germ cell. Observation: A case of MT of germ cell tumor in 17-year-old male into embryonal rhabdomyosarcoma is described. The histopathologic diagnosis was that of embryonal rhabdomyosarcoma in which no germ cell elements were found. The germ cell origin of transformed histology is supported by cytogenetic analysis (isochromosome 12p), and elevated alpha(1)-fetoprotein. Despite intensive therapy the patient died. Conclusions: MT of teratoma is rare entity with poor prognosis
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据