期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 17, 期 5, 页码 548-557出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2006.09.001
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Genetic engineering is entering a new era, where microorganisms can be programmed using synthetic constructs of DNA encoding logic and operational commands. A toolbox of modular genetic parts is being developed, comprised of cell-based environmental sensors and genetic circuits. Systems have already been designed to be interconnected with each other and interfaced with the control of cellular processes. Engineering theory will provide a predictive framework to design operational multicomponent systems. On the basis of these developments, increasingly complex cellular machines are being constructed to build specialty chemicals, weave biomaterials, and to deliver therapeutics.
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