Strontium promotes cell proliferation and suppresses IL-6 expression in human PDL cells

This study was designed to investigate the effect of strontium on human PDL cells in vitro. Strontium is used to treat osteoporosis because of its bone formation promoting effect on osteoblast cells. This investigation presents evidence that strontium promotes PDL cell proliferation. Simultaneously, strontium suppresses the expression of the inflammation-promoting cytokine IL-6. The observed effect of strontium on PDL cells supports its use it in guided dental tissue regeneration. (C) 2011 Elsevier GmbH. All rights reserved.