期刊
CHEMICAL SENSES
卷 31, 期 8, 页码 725-730出版社
OXFORD UNIV PRESS
DOI: 10.1093/chemse/bjl014
关键词
calcium; mouse; olfaction; pumps
资金
- NCRR NIH HHS [P20 RR16435, P20 RR016435] Funding Source: Medline
- NIDCD NIH HHS [R01 DC 00721, R21 DC006643-02, R21 DC006643, R01 DC000721, R01 DC006939, R01 DC 006939, R21 DC 006643] Funding Source: Medline
- PHS HHS [NCI PHS22435] Funding Source: Medline
We report here the presence of specific plasma membrane calcium pumps (PMCAs) in mouse olfactory sensory neurons. All 4 isoforms are present as shown by deconvolution microscopy, and the specific splice variants are identified by reverse transcriptase (RT)-polymerase chain reaction (PCR). The PMCAs are present on the cell body, dendrite, knob, and cilia, but the different isoforms of PMCAs are not identical in their distributions. The PMCAs are positioned to play a role in calcium clearance after stimulation.
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