期刊
JOURNAL OF CLINICAL MICROBIOLOGY
卷 44, 期 10, 页码 3826-3829出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00225-06
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- Medical Research Council [G0300403] Funding Source: researchfish
- MRC [G0300403] Funding Source: UKRI
- Medical Research Council [G0300403] Funding Source: Medline
The ability of fluorescence resonance energy transfer, molecular-beacon, and TaqMan probes to detect single nucleotide polymorphism (SNP) in the presence of a wild-type allele was evaluated using drug resistance-conferring SNPs in mixed Mycobacterium tuberculosis DNA. It was found that both the absolute quantity and the ratio of allelles determine the detection sensitivity of the probe systems.
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