Protein-based phylogenetic analysis by using hydropathy profile of amino acids

So far, various approaches for phylogenetic analysis have been developed. Almost all of them put stress on analyzing nucleic acid sequences or protein primary structures. In this paper, we take the physicochemical properties of amino acids into account and introduce the hydropathy profile of amino acids into phylogenetic analysis. We find that this introduction is effectual and our method may be used to complement phylogenetic analysis. (c) 2006 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.