期刊
NEURON
卷 52, 期 1, 页码 93-101出版社
CELL PRESS
DOI: 10.1016/j.neuron.2006.09.017
关键词
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资金
- NINDS NIH HHS [R01 NS34389, R01 NS40955] Funding Source: Medline
The importance of alternative splicing in the regulation of diverse biological processes is reflected in the growing list of human diseases associated with known or suspected splicing defects. It is becoming evident that alternative splicing plays a particularly important role in neurologic disease, which is perhaps not surprising given the important role splicing plays in generating complexity and function in the brain. This review considers the evidence that defects in regulation of splicing may underlie many types of human neurologic diseases.
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