期刊
JOURNAL OF THEORETICAL BIOLOGY
卷 242, 期 3, 页码 713-721出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jtbi.2006.04.023
关键词
viral capsid assembly; master equation; SV40 virus
资金
- Engineering and Physical Sciences Research Council [GR/S51936/01, GR/T26979/01] Funding Source: researchfish
The distribution of inequivalent geometries occurring during self-assembly of the major capsid protein in thermodynamic equilibrium is determined based on a master equation approach. These results are implemented to characterize the assembly of SV40 virus and to obtain information on the putative pathways controlling the progressive build-up of the SV40 capsid. The experimental testability of the predictions is assessed and an analysis of the geometries of the assembly intermediates on the dominant pathways is used to identify targets for anti-viral drug design. (c) 2006 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据