期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 50, 期 11, 页码 3893-3896出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00616-06
关键词
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Macrolide-resistant mutants of Campylobacter jejuni and Campylobacter coli were selected in vitro using erythromycin and tylosin. These mutants exhibited modifications in the ribosomal proteins L4 (G74D) and L22 (insertions at position 86 or 98). A synergy between the CmeABC efflux pump and these modifications in conferring macrolide resistance was observed.
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