期刊
NEUROIMAGING CLINICS OF NORTH AMERICA
卷 16, 期 4, 页码 619-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.nic.2006.06.005
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资金
- NCI NIH HHS [P01 CA 85878] Funding Source: Medline
Diffusion MR imaging techniques are based on the molecular mobility of water, which is sensitive to interaction with intracellular elements, macromolecules, cell membranes, the density of cells, and microstructural organization. Disease processes that alter cell-water homeostasis, cell density, and cyto architecture affect water mobility and are quantifiable by diffusion MR imaging methodologies. Similarly, therapeutic intervention that alters these properties may be monitored for efficacy via diffusion MR imaging. This article outlines basic technical concepts and applications of diffusion imaging with an emphasis on oncology.
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