Comorbidities in psoriasis

Psoriasis is a common inflammatory skin disease. Epidemiological data demonstrate an association with a number of distinct disorders of the joints (psoriatic arthritis), the intestine (Crohn's disease), and skin (pustular disorders), as well as increased risk of cardiovascular disease. Systemic risk factors include obesity, hypertension, dyslipidaemia and diabetes. There is evidence that chronic inflammation may be causative. For dermatologists it has become mandatory to closely monitor psoriasis patients for comorbidities. Early anti-inflammatory treatment regimens may prove to be preventive.