期刊
BRITISH JOURNAL OF PSYCHIATRY
卷 189, 期 -, 页码 461-462出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1192/bjp.bp.105.017335
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Avolition affects quality of life in chronic schizophrenia. We investigated the effect of modafinil upon unconstrained motor activity in 18 male patients. In a randomised crossover design study, wrist-worn actigraphic monitors were used to objectively record motor activity over a 20 h period. Patients' total activity was significantly greater when given the drug. These data suggest that modafinil increases quantifiable motor behaviour in schizophrenia and may have an impact on avolition.
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