期刊
NATURE NEUROSCIENCE
卷 9, 期 11, 页码 1362-1363出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nn1780
关键词
-
资金
- NIMH NIH HHS [R01 MH067602, MH64625, MH072837, K24 MH064625, MH067602, R01 MH079164] Funding Source: Medline
We examined the contribution of 5-HT1A autoreceptors ( with [ C-11] WAY100635 positron emission tomography) to amygdala reactivity ( with blood oxygenation level - dependent functional magnetic resonance imaging) in 20 healthy adult volunteers. We found a significant inverse relationship wherein 5-HT1A autoreceptor density predicted a notable 30 - 44% of the variability in amygdala reactivity. Our data suggest a potential molecular mechanism by which a reduced capacity for negative feedback regulation of 5-HT release is associated with increased amygdala reactivity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据