期刊
AUTOIMMUNITY REVIEWS
卷 6, 期 1, 页码 5-9出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.autrev.2006.03.002
关键词
TT virus; pathogenesis; autoimmunity; rheumatic disorders
类别
资金
- FIC NIH HHS [F05 TW05421] Funding Source: Medline
- NIAID NIH HHS [R01 AI48079] Funding Source: Medline
Pathogenesis of viral origin has long been suggested in autoimmune rheumatic diseases. Beside the well-defined virus induced transient or chronic rheumatic diseases often resembling systemic autoimmune disorders such as rheumatoid arthritis, viruses can contribute to disease pathogenesis by several different pathomechanisms. TT virus is a recently discovered virus of extremely high genetic diversity which commonly infects humans. Despite accumulated evidence on the biological characteristics of TTV, its pathogenecity is still in question; many consider TTV as harmless endosymbiont. The recent paper overviews the biology of TT virus and investigates the hypothesis that TTV might have a causative role in human diseases with special attention to the possibility that TTV might trigger autoimmunity in rheumatic disorders (c) 2006 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据