期刊
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
卷 65, 期 3, 页码 350-354出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ecoenv.2005.09.002
关键词
copper; EDTA; goldfish; copper content; antioxidant defense system
Copper bioavailability in the tissues of goldfish and antioxidant defenses in the liver of fish were investigated in vivo following 40 days of exposure to different species of copper solutions at different concentrations. Copper seemed to be more concentrated in the gill than in the liver after Cu(2+) and copper-ethylenediaminetetraacetate (Cu-EDTA) exposure. The addition of EDTA markedly affected copper adsorption in the gill but had no significant effects in the liver. We also found that in the fish exposed to the concentration Of Cu(2+) below the Chinese national fishery water quality standard of 0.01 mg/L, superoxide dismutase (SOD) and glutathione S-transferase (GST) activities in liver were stimulated and catalase (CAT) and Se-dependent glutathione peroxidase (Se-GPx) activities were inhibited after 40 days of exposure. Compared to copper exposure, the addition of EDTA did not affect SOD and GST significantly. However, CAT and GPx activity with Cu(2+) exposure were significantly different from those with Cu-EDTA exposure. (c) 2005 Elsevier Inc. All rights reserved.
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