The outcome of pregnancy following pre-pregnancy or early pregnancy alendronate treatment

In spite of a substantial increase in the use of bisphosphonates at child bearing age, very little is known regarding its use in pregnancy. We describe the outcome of 24 pregnancies after pre-pregnancy or early pregnancy alendronate therapy. Based on the pregnancy outcome it seems that alendronate does not impose a major teratogenic risk. (c) 2006 Elsevier Inc. All rights reserved.