期刊
MOLECULES
卷 11, 期 11, 页码 904-914出版社
MDPI
DOI: 10.3390/11110904
关键词
Schiff bases; antimicrobial activity; copper complexes; aminoantipyrine
The synthesis of Cu(II) complexes derived from Schiff base ligands obtained by the condensation of 2-hydroxybenzaldehyde or tereplitalic aldehyde with 4-amino-antipyrine (4-amino-2,3 -dimethyl-1-phenyl-3-pyrazolin-5-one) is presented. The newly prepared compounds were characterized by H-1-NMR, UV-VIS, IR and ESR spectroscopy. The determination of the antimicrobial activity of the ligands and of the complexes was carried out on samples of Escherichia coli, Klebsiella pneumoniae, Acinetobacter boumanii, Pseudomonas aeruginosa, Staphylococcus aureus and Candida sp. The qualitative and quantitative antimicrobial activity test results proved that all the prepared complexes are very active, especially against samples of Ps. aeruginosa, A. Boumanii, E. coli and S. aureus.
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