期刊
VISION RESEARCH
卷 46, 期 24, 页码 4163-4180出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.visres.2006.07.007
关键词
visual evoked potential; magnocellular; parvocellular; ON pathway; OFF pathway; contrast gain control; shunting inhibition; nonlinear model
资金
- NEI NIH HHS [EY02439, EY01428] Funding Source: Medline
Isolated-checks were luminance-modulated temporally to elicit VEPs. Bright or dark checks were used to drive ON or OFF pathways, and low or high-contrast conditions were used to emphasize activity from magnocellular or parvocellular pathways. Manipulation of stimulus parameters and frequency analysis of the VEP were performed to obtain spatial and contrast-response functions. A biophysical explanation is offered for why the opposite polarity stimuli drive selectively ON and OFF pathways in primary visual cortex, and a lumped biophysical model is proposed to quantify the data and characterize changes in the dynamics of the system with contrast given a limited number of parameters. Response functions were found to match the characteristics of the targeted pathways. (C) 2006 Elsevier Ltd. All rights reserved.
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