期刊
MICROBIOLOGY
卷 75, 期 6, 页码 644-648出版社
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S002626170606004X
关键词
filamentous fungi; permafrost ancient deposits; Penicillium; microcycle conidiation; biosynthesis; secondary metabolites; clavine alkaloids; rugulovasines
类别
It has been established that relict fungi Penicillium variabile Sopp can synthesize clavine alkaloids, rugulovasines A and B, which are revealed in this species for the first time. Submerged cultivation of the strain-producer revealed several microcycles of conidia formation. The synthesis of alkaloids was also of a cyclic character. The synchronism of cyclic rugulovasine biosynthesis and conidia formation was revealed. Zinc ions stimulated fungal growth but had a negative effect on the biosynthesis of rugulovasines.
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