期刊
BIOESSAYS
卷 28, 期 11, 页码 1072-1077出版社
WILEY
DOI: 10.1002/bies.20485
关键词
-
资金
- MRC [G0300415] Funding Source: UKRI
- Medical Research Council [G0300415] Funding Source: researchfish
- Medical Research Council [G0300415] Funding Source: Medline
The liver contains two systems for the removal of ammonia-the urea cycle and the enzyme glutamine synthetase. These systems are expressed in a complementary fashion in two distinct populations of hepatocytes, referred to as periportal and perivenous cells. One of the unresolved problems in hepatology has been to elucidate the molecular mechanisms responsible for induction and maintenance of the cellular heterogeneity for ammonia detoxification. There is now a potential molecular explanation for the zonation of the urea cycle and glutamine synthetase based on the Wnt/beta-catenin pathway.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据