CeCl3•7H2O:: an efficient and reusable catalyst for the preparation of β-acetamido carbonyl compounds by multi-component reactions (MCRs)

A convenient method for the preparation of beta-acetamido carbonyl compounds is described by multi-component reactions of aromatic aldehydes, enolizable ketones or beta-keto esters and acetonitrile in the presence of acetyl chloride and 10 mol % CeCl(3)(.)7H(2)O at room temperature. (c) 2006 Elsevier Ltd. All rights reserved.