期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 16, 期 22, 页码 5767-5772出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2006.08.088
关键词
stilbene derivatives; carbon-11; fluorine-18; positron emission; tomography (PET); aryl hydrocarbon receptor (AhR); cancer
资金
- NINDS NIH HHS [5P50NS052606] Funding Source: Medline
New carbon-11 and fluorine-18 labeled stilbene derivatives, cis-3,5-dimethoxy-4'-[C-11]methoxystilbene (4'-[C-11]8a), cis-3,4',5-trimethoxy-3'-[C-11]methoxystilbene (3'-[C-11]8b), trans-3,5-dimethoxy-4'-[C-11]methoxystilbene (4'-[C-11]10a), trans-3,4',5-trirnethoxy-3'-[C-11]methoxystilbene (3'-[C-11]10b), cis- 3,5-dimethoxy-4'-[F-18]fluorostilbene (4'-[F-18]12a), and trans-3,5-dimethoxy-4'-[F-18]fluorostilbene (4'-[F-18]13a), were designed and synthesized as potential PET probes for aryl hydrocarbon receptor (AhR) in cancers. (c) 2006 Elsevier Ltd. All rights reserved.
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