Pathological gambling secondary to dopaminergic therapy in Parkinson's disease

We describe six patients with Parkinson's disease (PD) and pathological gambling. All patients started gambling after the onset of PD and initiation or increase of treatment with dopaminergic therapy. The fact that pathological behaviour disappeared as medication was ended or decreased suggests that an elaborate behavioural manifestation could be related to dopamine tone in patients with Parkinson's disease. (c) 2006 Elsevier Ireland Ltd. All rights reserved.