期刊
JOURNAL OF INFECTIOUS DISEASES
卷 194, 期 10, 页码 1398-1402出版社
OXFORD UNIV PRESS INC
DOI: 10.1086/508551
关键词
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资金
- NIAID NIH HHS [R21 AI056118, AI55466, AI056118, U54AI57158, R01 AI051292, R21 AI055466, U54 AI057158, AI51292, U54 AI05715803, UC1 AI062705] Funding Source: Medline
- PHS HHS [U50/CCU223671] Funding Source: Medline
In New York State during winter 2004, there was a high incidence of influenza-like illness that tested negative both for influenza virus, by molecular methods, and for other respiratory viruses, by virus culture. Concern that a novel pathogen might be implicated led us to implement a new multiplex diagnostic tool. MassTag polymerase chain reaction resolved 26 of 79 previously negative samples, revealing the presence of rhinoviruses in a large proportion of samples, half of which belonged to a previously uncharacterized genetic clade. In some instances, knowledge of the detected viral and/or bacterial (co) infection could have altered clinical management.
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