期刊
TETRAHEDRON LETTERS
卷 47, 期 47, 页码 8387-8390出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.09.071
关键词
-
资金
- NIGMS NIH HHS [R01 GM059384, R01 GM059384-26] Funding Source: Medline
The decarbomethoxylation reaction of a substituted alpha-hydroxy-alpha-carbomethoxy pentacyclic substituted ketone, used as an advanced intermediate in the synthesis of the alkaloid aspidophytine, can be effected by heating with MgI2 in CH3CN. The reaction was shown to proceed by a novel a-hydroxy beta-dicarbonyl to alpha-ketol ester rearrangement. It was possible to isolate a carbonate intermediate in 75% yield, thereby providing support for the proposed pathway. (c) 2006 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据