期刊
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
卷 195, 期 6, 页码 1512-1520出版社
MOSBY-ELSEVIER
DOI: 10.1016/j.ajog.2006.01.074
关键词
preterm premature rupture of membranes; pregnancy outcome
资金
- NCRR NIH HHS [RR-03061, P20 RR011091, G12 RR003061, RR-11091] Funding Source: Medline
- NICHD NIH HHS [R01 HD024314, HD 24314] Funding Source: Medline
In view of the important protective role of the fetal membranes, wound scaling, tissue regeneration, or wound healing could be life saving in cases of preterm premature rupture of the membranes. Although many investigators are studying the causes of preterm premature rupture of membranes, the emphasis has not been on the wound healing capacity of the fetal membranes. In this review, the relevant literature on the pathophysiologic condition that leads to preterm premature rupture of membranes will be summarized to emphasize a continuum of events between rupture and repair. We will present the current knowledge on fetal membrane wound healing and discuss the clinical implications of these findings. We will critically discuss recent experimental interventions in women to seal or heal the fetal membranes after preterm premature rupture of membranes. (c) 2006 Mosby, Inc. All rights reserved.
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