Hormone replacement therapy

With many women in or near menopause and multiple news stories of hormone risks, there has been renewed interest in the treatment of menopause. Vasomotor symptoms or hot flashes occur in 14% to 51 % of women before menopause, in 35% to 50% in the perimenopausal period, and in 30% to 80% after menopause [1]. Menopause and its transition time also may cause vaginal dryness or painful intercourse, steep disturbances, mood changes, and other somatic complaints. Recent large studies have shown that hormone replacement therapy (HRT) should not be used for disease prevention and have shown risks that may offset their benefits. With the United States' baby-boom generation approaching menopause, many women are asking their doctors about the usefulness of HRT and whether they should use alternatives. This article reviews the studies that have shaped our current perspective and outlines the recommendations of major medical organizations.