期刊
CLINICS IN LABORATORY MEDICINE
卷 26, 期 4, 页码 751-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cll.2006.07.002
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资金
- NCRR NIH HHS [RR 019975] Funding Source: Medline
- NHLBI NIH HHS [HL 62705] Funding Source: Medline
Lipoprotein(a) (Lp(a)) is present in humans and primates. It has many properties in common with low-density lipoprotein, but Qcontains a unique protein moiety designated apo(a), which is linked to apolipoprotein B-100 by a single disulfide bond. International standards for Lp(a) measurement and optimized Lp(a) assays insensitive to isoform size are not yet widely available. Lp(a) is a risk factor for coronary artery disease, and smaller size apo(a) is associated with coronary artery disease. The physiologic role of Lp(a) is unknown.
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