期刊
SUICIDE AND LIFE-THREATENING BEHAVIOR
卷 36, 期 6, 页码 687-693出版社
WILEY
DOI: 10.1521/suli.2006.36.6.687
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There is growing evidence that a functional polymorphism in the serotonin transporter gene (5-HTTLPR) moderates the impact of negative life events (e.g., childhood abuse) on the development of depression. However, it is unclear whether the gene x environment interaction predicts suicide attempts specifically. In addition, previous studies have not examined different forms of childhood abuse separately. In the current study, we found that 5-HTTLPR genotype moderated the link between childhood physical and sexual, but not emotional, abuse and adult psychiatric inpatients' histories of suicide attempts.
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