期刊
EUROPEAN JOURNAL OF NEUROSCIENCE
卷 24, 期 11, 页码 3265-3270出版社
BLACKWELL PUBLISHING
DOI: 10.1111/j.1460-9568.2006.05195.x
关键词
amphetamine; blocking; context; fear; rat
资金
- Wellcome Trust [063095/Z/00/Z] Funding Source: Medline
Associative learning depends on the discrepancy between actual and predicted outcomes. The neurochemical mechanisms involved in regulating this discrepancy in Pavlovian fear conditioning in rats are unknown. We employed the blocking paradigm to show that this learning discrepancy is decreased by heightened activation of dopamine following an accumbal infusion Of D-amphetamine, and increased by dopaminegic blockade following an accumbal infusion of cis-(z)-flupenthixol or by combined infusions of the D1 (SCH23390) and D2 (sulpiride) antagonists but not by infusion of either alone.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据