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Peptides targeting protein kinases: Strategies and implications

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PHYSIOLOGY
卷 21, 期 -, 页码 411-418

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AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00022.2006

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Protein kinases are important key regulators in most, if not all, biological processes and are linked with many human diseases. Protein kinases thus became attractive targets for drug design. Intracellularly active peptides that selectively interfere with kinase function and or kinase-mediated signaling pathways are potential drug compounds with therapeutic implications.

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